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ADP 6-0 uses joint terms where applicable. Selected joint and Army terms and definitions appear in both the glossary and the text. Terms for which ADP 6-0 is the proponent publication (the authority) are marked with an asterisk (.) in the glossary. Definitions for which ADP 6-0 is the proponent publication are boldfaced in the text.

Does this test have other names?

  1. FM 6-0, C1 Change No. 1 Headquarters Department of the Army Washington, DC, 11 May 2015 Commander and Staff Organization and Operations 1. Change 1 to FM 6-0, 5 March 2014, adds the supersession statement to the cover. Modifies figure 7-2. Modifies figure 9-5. Adds joint command relationships to appendix B.
  2. LibreOffice Productivity Suite 7.0.2 8 similar apps in Office Applications Acronis True Image Home 2021 25.5.1 3 similar apps in Backup Prey 1.9.6 Filed in Security.

CD4/CD8 ratio T-cell test

What is this test?

This test looks at the ratio of two important types of white blood cells in your blood.

Lymphocytes are a type of white blood cell in your immune system. This test looks at two of them, CD4 and CD8. CD4 cells lead the fight against infections. CD8 cells can kill cancer cells and other invaders.

If you have HIV, your CD4 cell count may be low. Without HIV treatment, your number of CD4 cells will likely keep falling. A lack of CD4 cells usually leads to more frequent infection.

This test looks at the ratio of CD4 cells to CD8 cells. The ratio tells your healthcare provider how strong your immune system is and helps predict how likely you are to develop a crippling infection.

In addition to HIV/AIDS, conditions that can be monitored with this test include infectious mononucleosis and other viral infections, chronic lymphocytic leukemia, Hodgkin disease, aplastic anemia, and neurological disorders like multiple sclerosis and myasthenia gravis.

Why do I need this test?

You may need this test if your healthcare provider thinks you have HIV. Some people infected with HIV may develop flu-like symptoms within a few weeks of getting the virus. But other people have no symptoms at all.

Although the test looks at the ratio of CD4 cells to CD8 cells, your healthcare provider may focus on the results of the CD4 count.

You may also have this test to see how well HIV treatment is working.

What other tests might I have along with this test?

Your healthcare provider may also order other tests to help diagnose HIV. These include:

  • HIV test

  • Complete blood count

What do my test results mean?

Many things may affect your lab test results. These include the method each lab uses to do the test. Even if your test results are different from the normal value, you may not have a problem. To learn what the results mean for you, talk with your healthcare provider.

Results for the ratio are given as a number. The results for each cell count are given as a number per cubic millimeter (/mm3).

A normal CD4/CD8 ratio is 2.0, with CD4 lymphocytes equal to or greater than 400/mm3 and CD8 lymphocytes equal to 200 to 800/mm3.

If your ratio is higher than 2, it means your immune system is strong and you may not have HIV.

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If your ratio is less than 1, you may have:

  • HIV

  • AIDS if your CD4 count is less than 200/mm3

  • Bone marrow problems related to chemotherapy

  • Anemia

  • Multiple sclerosis, myasthenia gravis, or another nervous system condition

  • Chronic infection

Higher than normal results may mean you have:

  • Major infection

  • Viral infection

  • Type of blood cancer

How is this test done?

The test requires a blood sample, which is drawn through a needle from a vein in your arm.

Does this test pose any risks?

Taking a blood sample with a needle carries risks that include bleeding, infection, bruising, or feeling dizzy. When the needle pricks your arm, you may feel a slight stinging sensation or pain. Afterward, the site may be slightly sore.

What might affect my test results?

Pregnancy can affect your results. Women with HIV may have higher levels of white blood cells, which affects the proportion of CD4 cells. Drinking too much alcohol can also affect your results. Certain medicines such as corticosteroids can affect your results.

How do I get ready for this test?

You don't need to prepare for this test. But tell your healthcare provider if you are pregnant, are a heavy alcohol user, or are taking medicines that could affect your white blood cell count. In addition, be sure your provider knows about all medicines, herbs, vitamins, and supplements you are taking. This includes medicines that don't need a prescription and any illicit drugs you may use.

Entity Framework is Microsoft's recommended data access technology for new applications.

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Version History

VersionDownloadsLast updated
6.4.4 1,604,996 5/12/2020
6.4.0 3,578,232 12/3/2019
6.4.0-preview3-19553-01 25,708 11/13/2019
6.4.0-preview2-19525-03 8,230 11/1/2019
6.4.0-preview1-19506-01 18,937 10/15/2019
6.3.0 3,059,864 9/23/2019
6.3.0-rc1-19458-04 4,698 9/16/2019
6.3.0-preview9-19423-04 9,103 9/4/2019
6.3.0-preview8-19405-04 14,775 8/13/2019
6.3.0-preview7-19363-02 29,363 7/23/2019
6.3.0-preview6-19304-03 31,694 6/12/2019
6.3.0-preview5-19254-05 23,505 5/7/2019
6.2.0 24,589,762 10/26/2017
6.2.0-beta1 201,381 5/19/2017
6.1.3 34,172,291 3/10/2015
6.1.3-beta1 210,831 2/11/2015
6.1.2 2,530,209 12/22/2014
6.1.2-beta2 74,779 11/14/2014
6.1.2-beta1 147,818 9/18/2014
6.1.1 5,009,750 6/20/2014
6.1.1-beta1 74,817 5/20/2014
6.1.0 4,452,443 3/17/2014
6.1.0-beta1 98,870 2/11/2014
6.1.0-alpha1 86,157 12/20/2013
6.0.2 2,274,097 12/13/2013
6.0.2-beta1 74,528 11/27/2013
6.0.1 1,364,180 10/17/2013
6.0.0 6,363,592 10/17/2013
6.0.0-rc1 114,348 8/21/2013
6.0.0-beta1 125,426 5/28/2013
6.0.0-alpha3 79,849 2/25/2013
6.0.0-alpha2 73,429 12/10/2012
6.0.0-alpha1 57,670 10/25/2012
5.0.0 10,432,856 8/11/2012
5.0.0-rc 185,842 5/15/2012
5.0.0-beta2 37,088 3/22/2012
5.0.0-beta1 43,146 2/29/2012
4.3.1 628,448 2/29/2012
4.3.0 135,180 2/9/2012
4.3.0-beta1 23,507 1/13/2012
4.2.0 477,450 11/1/2011
4.1.10715 852,090 7/25/2011
4.1.10331 920,236 4/12/2011
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